|
Symbol Name ID |
Agtr1a
angiotensin II receptor, type 1a MGI:87964 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Keratoconjunctivitis sicca |
Premature coronary artery atherosclerosis |
Abnormal cardiac ventricular function |
Elevated diastolic blood pressure |
Elevated mean arterial pressure |
Elevated systolic blood pressure |
Hypertension |
Portal hypertension |
Arrhythmia |
Sudden cardiac death |
Ventricular tachycardia |
Heart block |
Myocardial infarction |
Abnormal lymph node morphology |
Lymphadenopathy |
| Disease(s) Associated with AGTR1 | |||||||||||||||
| coronary artery disease | |||||||||||||||
| essential hypertension | |||||||||||||||
| sarcoidosis |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal kidney interlobular artery morphology |
abnormal kidney vasculature morphology |
abnormal heart morphology |
increased heart atrium size |
decreased heart weight |
increased heart weight |
enlarged heart |
heart hyperplasia |
abnormal heart left ventricle morphology |
cardiac fibrosis |
cardiac interstitial fibrosis |
abnormal cardiovascular system physiology |
abnormal heart rate |
decreased heart rate |
abnormal impulse conducting system conduction |
prolonged PR interval |
atrioventricular block |
prolonged QRS complex duration |
abnormal systemic arterial blood pressure |
decreased systemic arterial blood pressure |
decreased mean systemic arterial blood pressure |
decreased systemic arterial systolic blood pressure |
hypotension |
increased systemic arterial blood pressure |
increased systemic arterial systolic blood pressure |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Agtr1aem1(IMPC)Rbrc/Agtr1aem1(IMPC)Rbrc | |||||||||||||||||||||||||||
| Agtr1atm1Afu/Agtr1atm1Afu | |||||||||||||||||||||||||||
| Agtr1atm1Ecl/Agtr1atm1Ecl | |||||||||||||||||||||||||||
| Agtr1atm1Tma/Agtr1atm1Tma | |||||||||||||||||||||||||||
| Agtr1atm1Unc/Agtr1atm1Unc | |||||||||||||||||||||||||||
| Agtr1atm2Tma/Agtr1atm2Tma | |||||||||||||||||||||||||||
| Agtr1atm1Afu/Agtr1a+ | |||||||||||||||||||||||||||
| Agtr1atm1Unc/Agtr1a+ | |||||||||||||||||||||||||||
| Tg(Myh6-Agtr1a)4-7Vjd/0 | |||||||||||||||||||||||||||
| Agtr1atm1.1Cof/Agtr1atm1.1Cof Hprt1tm1(Pck1-cre)Vhh/Hprt1+ (conditional) |
|||||||||||||||||||||||||||
| Agtr1atm1Uky/Agtr1atm1Uky Tg(Tagln-cre)1Her/0 (conditional) |
* | ||||||||||||||||||||||||||
| Agtr1atm3Tma/Agtr1atm3Tma Tg(Nphs1-cre)10Mska/0 (conditional) |
* | ||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|
|
||
Analysis Tools